Microfluidic Technologies for Human Health
The field of microfluidics has in the last decade permeated many disciplines, from physics to biology and chemistry, and from bioengineering to medical research. One of the most important applications of lab-on-a-chip devices in medicine and related disciplines is disease diagnostics, which involves...
| Основен автор: | Demirci, Utkan. |
|---|---|
| Други автори: | Khademhosseini, Ali., Langer, Robert. |
| Формат: | Електронен |
| Език: | English |
| Публикувано: |
Singapore :
World Scientific,
2012.
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| Предмети: | |
| Онлайн достъп: |
http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=525629 |
| Подобни документи: |
Print version::
Microfluidic Technologies for Human Health. |
Съдържание:
- Preface; List of Contributors; Chapter 1 A Microscale Bioinspired Cochlear-like Sensor Robert D. White, Robert Littrell, and Karl Grosh; Introduction; Physiology and Design; Microfabrication; Experimental Results; Mathematical Modeling; Conclusions; Acknowledgment; References; Chapter 2 Systematic Evaluation of the Efficiencies of Proteins and Chemicals in Pharmaceutical Applications Morgan Hamon and Jong Wook Hong; Introduction; Microbioreactors for Drug Target Selection; Proteomics and genomics; Metabolomics; Microfluidic Devices for Compound Generation.
- Lead Identification in Microfluidic SystemsProtein crystallization; Identification of "hit" compounds; Droplet-based microfluidic devices for HTS; Microdevices Useful in Lead Optimization Processes; Dose-response analysis and IC50 measurement; ADME/Tox evaluation; Summary and Perspectives; Acknowledgments; References; Chapter 3 Microfluidic Glucose Sensors Jithesh V. Veetil, Sruthi Ravindranathan, Sha Jin, and Kaiming Ye; Introduction; Classification of Microfluidic Glucose Sensors Based on their Fabrication Methods; Lab-on-a-chip; Lab-on-a-paper; Lab-on-a-disk.
- Enzyme-based Microfluidic Glucose SensorsAmperometric glucose sensors; Enzyme-based optical microfluidic glucose sensors; Enzymatic glucose sensors with integrated sampling systems; Enzyme-free Glucose Detection Systems; Microfluidic glucose sensors on carbon nanotubes; Microfluidic glucose sensors on paper and foil; Challenges and Prospectives; References; Chapter 4 Applications of Microfabrication and Microfluidic Techniques in Mesenchymal Stem Cell Research Abhijit Majumder, Jyotsna Dhawan, Oren Levy, and Jeffrey M. Karp; Introduction.
- Mesenchymal stem cells and their importance in regenerative medicineChallenges in MSC research and the role of microfabrication and microfluidics; Microfabrication: Cell-adhesive islands and micro-/ nanotopography; Micropatterning of cell-adhesive islands; Effect of cell size; Effect of cell shape; Effect of substrate topology on MSC fate; Importance of topography; Role of microfabrication; Artificially created topology: Structures and materials; Structures; Materials; Micro-/nanogrooves; Effect of pattern size on MSC cytoskeleton, morphology, and alignment.
- Effect of pattern size on MSC differentiationEffect of pattern size on proliferation; Micro-/nanopits: Effect of disorder; A few other shapes: Effect of shape; Substrates with micropillars; Nanotubes and nanowires; Application of Microfluidics; Importance of flow in cell biology; Advantages of microfluidics; Problems of microfluidics; Microfluidics in MSC research; Conclusions and Outlook; Suggested Reviews; Stem cells and MSCs; Microscale techniques and biology; Mechanotransduction; Micropatterning; Effect of topology; Microfluidics; Acknowledgement; References.