Applications of toxicogenomics in safety evaluation and risk assessment /
"This book provides a timely overview of toxicogenomics, with special emphasis on the practical applications of this technology to the risk assessment process. Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in info...
| Други автори: | Boverhof, Darrell R., Gollapudi, B. Bhaskar. |
|---|---|
| Формат: | Електронна книга |
| Език: | English |
| Публикувано: |
Hoboken, N.J. :
John Wiley & Sons,
℗♭2011.
|
| Предмети: | |
| Онлайн достъп: |
http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=390128 |
| Подобни документи: |
Print version::
Applications of toxicogenomics in safety evaluation and risk assessment. |
Съдържание:
- Toxicology, "omics" technologies, and toxicogenomics : a primer
- Introduction to human health risk assessment
- Practical considerations for the application of toxicogenomics to risk assessment
- early experience, current drivers, and a path forward
- Approaches and practical considerations for the analysis of toxicogenomics data
- Genomics in identifying mutagenic mode of action in carcinogenesis
- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens
- Genomics in characterizing endocrine toxicity
- Studying organ specific toxicity using gene expression profiling
- Toxicogenomic studies in human populations
- Toxicogenomics applied to ecological risk assessment
- Analysis of transcriptomic dose response data for toxicology and risk assessment
- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges
- Toxicogenomics and animal alternatives
- Toxicogenomics and the regulatory framework
- Standardization of gene expression information for the safety evaluation
- activities in Japan
- Applying transcriptional profiling in drug safety evaluation
- Reframing the risk assessment paradigm : towards a systems biology approach.